World Parkinson's Disease Day: Role of Genetics and Environment in Parkinson's Disease
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While genetics play a role in Parkinson's disease, it is likely that environmental factors play a more significant role in the vast majority of cases. Common type of Parkinson’s disease like sporadic type, without family history probably results from a complex interaction of genetic and environmental factors Parkinson’s disease is one of the commonest neurodegenerative disorders in the world and India. Age is the single most risk factor for Parkinson’s disease, seen commonly after the age of 60, and the prevalence of PD is increasing as the life expectancy of the population increases. Common type of Parkinson’s disease which is sporadic type, without family history probably results from a complex interaction of genetic and environmental factors. Some of the alterations in genes like GBA, UCHL1 etc that can increase the risk of developing Parkinson’s disease. “Whereas approximately 15% of PD are familial PD, where definite causative genetic mutations have been identified