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Amblyopia: Study Claims Lazy Eye Puts Children At Higher Risk In Adulthood

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[ad_1] According to a new study performed by UCL researchers, those who had amblyopia ('lazy eye') in childhood are more likely to experience hypertension, obesity, and metabolic syndrome in adulthood, as well as an increased risk of heart attacks. In publishing the study in eClinicalMedicine, the authors stress that while they have identified a correlation, their research does not show a causal relationship between amblyopia and ill health in adulthood. The researchers analysed data from more than 126,000 participants aged 40 to 69 years old from the UK Biobank cohort, who had undergone ocular examination. Participants had been asked during recruitment whether they were treated for amblyopia in childhood and whether they still had the condition in adulthood. They were also asked if they had a medical diagnosis of diabetes, high blood pressure, or cardio/cerebrovascular disease (ie. angina, heart attack, stroke). Meanwhile, their BMI (body mass index), bloo...

Protein droplets may cause many types of genetic diseases: Research - Times of India

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[ad_1] BERLIN: Most proteins are found in separate protein-rich droplets called "cellular condensates" in cells. These proteins carry sequence characteristics that serve as address labels, informing the protein which condensates to move into. Proteins may wind up in the wrong condensate if the labels are messed up. According to a multinational team of clinical medicine and fundamental biology researchers, this could be the source of many unresolved disorders . The findings were published in the journal Nature. Patients with BPTA syndrome have characteristically malformed limbs featuring short fingers and additional toes, missing tibia bones in their legs and reduced brain size. As the researchers found out, BPTAS is caused by a special genetic change that causes an essential protein to migrate to the nucleolus, a large proteinaceous droplet in the cell nucleus. As a result, the function of the nucleolar condensate is inhibited and developmental disease develops. ...

Gum Disease Signs: Gum disease is linked to heart problems; learn to recognize signs and ways of preventing gum disease | The Times of India

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