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[ad_1] The scientific understanding of why some people are more susceptible to allergies than others is being strengthened by new studies. The University of Pennsylvania's Perelman School of Medicine researchers discovered how genetic variations that change a particular protein called ETS1 can affect how our bodies react to allergens. They discovered that in an animal model, even minor alterations in ETS1 can enhance the likelihood of allergic reactions that result in inflammation. The results were reported in Immunity. Allergies are the sixth most common cause of chronic illness in the United States, according to the Centers for Disease Control and Prevention, costing the country more than USD 18 billion annually.  It is still unknown how our DNA can alter our chances of acquiring an allergy, despite the fact that prior research has proven a strong genetic basis for allergies and discovered specific genetic sequence differences that predispose for these chronic diseases.