Obesity linked to neurodegeneration through insulin resistance, find researchers - Times of India
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CALIFORNIA: Researchers at the Fred Hutchinson Cancer Research Centre in the United States, led by Mroj Alassaf, have established a relationship between obesity and neurodegenerative illnesses like as Alzheimer's disease. The study, which used the common fruit fly, found that a high-sugar diet -- a hallmark of obesity -- induces insulin resistance in the brain, which lowers the ability to eliminate neuronal debris, raising the risk of neurodegeneration . The study, which was published in the open access journal PLOS Biology, will have an impact on medications meant to minimise the chance of acquiring neurodegenerative illnesses. Although obesity is known to be a risk factor for neurodegenerative disorders like Alzheimer's disease and Parkinson's disease, exactly how one leads to the other remains a mystery. The new study focused on answering this question by taking advantage of the similarity between humans and fruit flies. Having previously shown that a hig...