Do you know presence of healthy cells enables cancer to resist treatment? Study finds - Times of India
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WASHINGTON: Chemotherapy becomes less effective as healthy cells encourage cancer cells to grow more slowly, according to two studies from UCL and Yale. Researchers used mini-tumours' and the newest single-cell analysis technology to begin to unravel the conundrum of why healthy cells in a patient's colon cancer tumour may contribute to poor outcomes in the two experiments, which were funded by Cancer Research UK and published in Cell. Bowel cancer kills over 900,000 people a year and is the second highest cause of cancer mortality worldwide. In the UK, it accounts for 10% of all cancer deaths. In the first study, UCL researchers used the latest single-cell analysis technologies to measure how 1,107 mini-tumours derived from mice responded to changes in both their genes and their environment1. Analysis revealed that bowel cancer cells can exist in two major states, fast-growing or slow-growing, and that healthy cells can push bowel cancer cells towards the slow-g